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The project was headed up Nancy Thornberry, a biologist, and Ann Weber, a chemist (figure 34)

In addition, certain medical conditions and medications can cause vitamin B12 deficiency (30)

In fact, the GLP- 1 receptor-cAMP-PKA axis stimulates the growth of beta cells by activating the transducer of regulated cAMP response element-binding protein (CREB) (TORC2) and the expression of the CREB and insulin receptor substrate 2 genes [57] Additionally, by boosting bcl- 2 activity and blocking the proapoptotic Bax, activated CREB also supports beta cell survival [58]

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