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Similarly, we find that significant changes in DNA methylation that occur during the acute stress protocol (post-stress compared to pre-stress) can be associated with psychological stress reactivity but not cortisol reactivity

showing that even concentrations of a few mol (about 1.7 mol) increase in serum bilirubin reduce the risk of numerous pathological conditions ( 39 )

4 The significance of bilirubin in clinical practice and prognostic models derived from it The above article describes the association of bilirubin with some cancers, which naturally leads to the question of whether bilirubin can be used as a way to optimize bilirubin-related cancer treatment and patient stratification, but it has been shown that, while individual serum markers are useful prognostic factors in the study of patients with cancer, individual markers may not be sufficient for predicting survival in the clinical setting