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Expected Treatment Approach: Injection Sites: Typically administered in the abdomen, thigh, or back of the upper arm, rotating sites weekly

Lactulose to mannitol ratio in humans The ratio of urinary excretion of lactulose to mannitol (LA/MA) was used to measure the intestinal mucosal permeability in ten RA patients and ten healthy controls who underwent colonoscopy, with higher ratios indicative of increased intestinal permeability as previously described 33

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