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Estrogens could positively affect dopamine neurotransmission by reducing the expression of catechol-O-methyltransferase (COMT), the enzyme responsible for dopamine degradation (Jiang et al., 2003)

In human autopsy material from ALS patients, there is significant accumulation of CD4 + and CD8 + T-lymphocytes in the spinal cord along with activated microglia, astrocytes, and deposits of IgG, presumably produced by plasma cells ([24, 33, 141, 142]

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The GSH oxidized activity of glutathione peroxidase (GPx) was expressed as mole/minute/mg of protein [15]