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As a result, incretins can exert their physiological effects of boosting insulin secretion and reducing glucagon secretion, which ultimately leads to lower blood glucose levels

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[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Narendra D, Tanaka A, Suen DF, Youle RJ

These mechanisms may have either direct effect on organelles like mitochondria, endoplasmic reticulum, the cytoskeleton, microtubules and nucleus or indirect effect on cellular organelles through the activation and inhibition of signalling kinases, transcription factors and gene-expression profiles