Marchetti P, Castedo M, Susin SA, Zamzami N, Hirsch T, Macho A, Haeffner A, Hirsch F, Geuskens M, Kroemer G (1996) Mitochondrial permeability transition is a central coordinating event of apoptosis
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The tolerability profile appeared favorable for the vast majority completing the study period
But this may not be the first and only flop we see with this drug class.