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The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) flow diagram of the selection process is shown in Figure 2

A sex difference in cognition has also been observed in newly diagnosed MS patients, where males show increased anxiety and depression scores, and poorer attention compared to females (34)

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[5] [6] The medication carries a boxed warning regarding thyroid C-cell tumors observed in rodent studies and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2)