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Diabetes, glucose intolerance, and retinopathy history need clinician-guided review
In 2-year rat carcinogenicity studies referenced in the Increlex label, increased mammary and skin tumor incidence occurred at high IGF-1 exposure
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Approval status (mixed): Tesamorelin (Egrifta / Egrifta SV) is FDA-approved, but only for HIV-associated lipodystrophy body-composition, muscle and anti-aging use is off-label
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