The bovine protein alpha-lactalbumin increases the plasma ratio of tryptophan to the other large neutral amino acids, and in vulnerable subjects raises brain serotonin activity, reduces cortisol concentration, and improves mood under stress
Combine those downsides and endurance performance may actually decline, Kovacs said
(Source 4) "Supplementing with B vitamins can help correct deficiencies and promote nerve repair." It's important to note that metformin, a primary diabetes medication, depletes vitamin B12 levels, which can contribute to neuropathy
Wijayasinghe YS, Bhansali MP, Borkar MR, Chaturbhuj GU, Muntean BS, Viola RE, Bhansali PR (2022) A comprehensive biological and synthetic perspective on 2-deoxy-d-glucose (2-DG), a sweet molecule with therapeutic and diagnostic potentials