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**Reduction in Fatty Liver Disease**: Weight loss with these medications often leads to decreased liver fat, potentially improving or reversing non-alcoholic fatty liver disease[3]

Glover received consulting fees from Blueprint Medicine, Janssen, BMS, AbbVie, and Takeda

GLP-1s are used as part of a broader health strategy that includes lifestyle changes and other medications as needed: Metabolic-first lifestyle support: Hone recommends a protein-forward whole foods diet and limiting ultra-processed foods to help stabilize blood sugar and prevent the insulin spikes that can damage arteries

Elevated activity of mTORC1 is implicated with increased neuronal excitability