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For each case profile, we randomly sampled 1 patient visit from the subset of test set IV visits that match the profile, while ensuring diversity and representation across secondary criteria covering (a) drug classes in active prescription, (b) number of comorbidities and (c) types of comorbidities

This result is in accordance with a previous report that a GLP-1 analog (exendin-4) enhanced excitatory synaptic transmission through AMPA receptors trafficking in the PVN CRH neurons (16) (Figure 1, G and H)

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Both figures are legitimate, but they answer different statistical questions