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Secondly, since cardiomyocytes are easily affected by free iron overload, the release of excess free iron during ferroptosis would result in up-regulation of transferrin receptor (TFR) and down-regulation of ferritin, promoting cardiomyocyte cell death through mitochondrial VDAC2/3 or membrane lipid peroxidation through Fenton reaction to induce myocardial edema and dysfunction (Liu et al., 2018)
Additionally, a reduction in MDA levels and an increase in the activity of antioxidant enzymes, specifically SOD, GSH and CAT, were observed in the joint tissues of the rats
On the other hand, chitosan [25], lysozyme [26], bioprotection [27], ultra-high pressure homogenization [28], ozone [29], and, more recently, fumaric acid [30] have been proposed for protecting wine against microbiological spoilage
Which Foods are High in Histamine
