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34 The authors showed that the exposure of the isolated enzyme to the oxidant ONOO leads to a disruption of the zincthiolate cluster, resulting in an uncoupling of the enzyme

In infants diagnosed with AD, thiols have been found to be significantly reduced compared to in comparison to healthy controls, while disulfide levels were markedly elevated, indicative of dysregulation in the thiol/disulfide balance favoring peroxidation ( 3.4.3 Biopyrrin Biopyrrin is a metabolite derived from the oxidation of bilirubin

M.MirhosseiniY.KhaksariM.et al (2021)

Pro-inflammatory cytokine reduction: It decreases the production of IL-1, IL-6, IL-8, and TNF-, the main mediator molecules of inflammation