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These include pathways related to DNA repair, antioxidant defense, and tissue regeneration, as well as reduced expression of genes associated with inflammation and matrix degradation

In this phase II trial involving 50 men with metastatic castration-resistant prostate cancer (mCRPC), the administration of docetaxel combined with oral curcumin (6 g/day for 7 days every 3 weeks) demonstrated no significant differences in progression-free survival (PFS), PSA response, overall survival, or quality of life (QoL) when compared with placebo, despite high compliance and confirmed curcumin absorption

Jiang, X., Lin, W., Cheng, Y

Vitamin B12, folate, and the methionine remethylation cycle