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Thus, drastic metabolic alterations are expected to inevitably follow AR inhibition and re/activation during the progression to lethal CRPC along with AR antagonism therapy

Geria, MD FAAD is a board-certified dermatologist specializing in medical, surgical, and cosmetic dermatology

In AD, mitochondrial abnormalities, including impaired electron transport chain function and reduced mitochondrial biogenesis, lead to increased ROS production and diminished ATP generation

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