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Many athletes take a creatine supplement to help reduce fatigue, improve recovery and enhance performance

co-administration studies remain a relatively small subset

12 (10), e007598

In addition, a -rich supplement can increase neuromuscular performance during strenuous resistance training ( 2 ) administration probably enhance cytosolic Ca 2+ without changing force generation at a supraphysiological partial pressure of oxygen (PO 2 ) (60), or decrease cytosolic Ca 2+ along with less submaximal, but not maximal, force at a physiological PO 2 (61) (during isometric contractions stimulated in isolated rat muscle fibers)