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Prescribing information for GLP-1 receptor agonists indicates that these medications should not be used by individuals with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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OMV gets transferred to renal tubulointerstitial regions, where they promote the expression of inflammatory factors such as IL-1, TNF-, monocyte chemotactic protein (MCP)-1 and IL-6 in the renal tubulointerstitial cells through the Caspase-11 pathway, thus inducing tubulointerstitial inflammation

Make sure you're hitting adequate protein and nutrients - the appetite suppression from semaglutide can make it easy to under-eat protein