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Disruptions in calcium ion metabolism by iron overload in cardiomyocytes are thought to contribute to cardiac dysfunction in such patients (37), while heart fibrosis does not appear to be involved (38)

Duration depends on your goals, response, and a providers clinical recommendation

LunardonGde Oliveira SilvaTLinoCALuYWMirandaJBAsprinoPFet alSet7 deletion attenuates isoproterenol-induced cardiac fibrosis and delays cardiac dysfunction