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J Biol Chem 275:3938539393 Campisi J, di Fagagna F d A (2007) Cellular senescence: when bad things happen to good cells

This can lead to complications like an excess of fluid in the body, imbalances of the bodys salts (electrolytes), issues with metabolism, and changes to the bodys normal functions

Mice receiving AcSDKP 48 hours before DOX had increased HPP-CFC counts on days 14 and 18