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10.1002/jcp.28372 203 Rodriguez-JimenezF
These reversible modifications are playing essential roles in gene regulation, X-inactivation, imprinting, and silencing of parasitic DNA elements ( PATHOLOGICAL ALTERATIONS OF GSTP1 METHYLATION PATTERNS DNA methylation, the addition of a methyl-group to cytosines is the most common epigenetic modification, inducing the reorganization of the gene locus and thus regulating gene expression (Smith and Meissner, 2013)
However, adipocyte Ndufs2 KO mice had reduced WAT mass, increased liver mass, visceral adipocyte hypertrophy and impaired glucose tolerance (Fig
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