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PDB codes of previously published structures used in this study are 4HJE (human p53 DBD), 3L2C (human FOXO4 FH domain bound to DNA) and 1E17 (human FOXO4 FH domain)

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Glutathione may be responsible for several vital roles within a cell besides antioxidation: Maintenance of the redox state (chemical reactions in which the oxidation state of atoms are modified) Modulation of the immune response Detoxification of foreign bacteria and viruses Glutathione and chronic disease: Research has demonstrated that Glutathione deficiency may be a factor in many chronic conditions

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