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Katoh Y, Itoh K, Yoshida E, Miyagishi M, Fukamizu A, Yamamoto M

GSH is primarily synthesized intracellularly through two consecutive reactions catalyzed by -glutamylcysteine synthetase (Gsh1 in eukaryotes and GshA in prokaryotes, encoded by GSH1 and gshA , respectively) and glutathione synthetase (Gsh2 in eukaryotes and GshB in prokaryotes, encoded by GSH2 and gshB , respectively)

Our study illustrates the importance of studying ciliopathies, not only as rare genetic disorders but also as critical contributors to metabolic dysregulation in more prevalent forms of obesity

[We] must always weigh the medical risks against the benefits when taking a medication."