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B12 supplementation is especially beneficial for those following plant-based diets who may have difficulty getting enough of this vitamin from food sources

LiuHSridharVBouletJDhariaAKhanALawlerPet alCardiorenal protection with SGLT2 inhibitors in patients with diabetes mellitus: From biomarkers to clinical outcomes in heart failure and diabetic kidney disease

PLoS ONE 8 , e77060 (2013)

Patients pairing GLP-1 therapy with HRT may experience: Greater total weight and fat loss compared to GLP-1 therapy alone Improved body composition and muscle tone Enhanced energy and daily performance More consistent, lasting results Clinical insights suggest that addressing hormonal imbalances alongside GLP-1 therapy may lead to up to 30% greater weight loss in appropriate candidates