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1,2 As scientists continue to investigate established and new therapeutic applications, GLP-1 receptor (GLP-1R) agonists such as semaglutide, dulaglutide, and tirzepatide have become increasingly relevant tools in preclinical research

Potential antagonistic effects Conversely, curcumin has been shown to interfere with the action of other chemotherapeutic drugs (e.g., cyclophosphamide, doxorubicin) by activating certain detoxification pathways (like ABC transporters) that pump the drugs out of cancer cells, thereby reducing their effectiveness (244)

The goal is to help patients use GLP-1 therapy safely and effectively with medical supervision