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In parallel, advances in peptide chemistry and structural biology have enabled the design of aggregation inhibitors, receptor-selective neuropeptide analogues, and cell-penetrating or brain-targeted peptide conjugates that modulate key pathways, including proteostasis, insulin and incretin signaling, neurotrophic support, and microglial activation

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While topical products may be adequate for mild surface-level concerns, addressing established skin laxity with significant collagen and elastin loss typically requires the higher tissue concentrations achievable through injection

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