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Dihydroxyacetone induces G2/M arrest and apoptotic cell death in A375P melanoma cells

While its exact cause remains unclear, IBS is increasingly understood as a multifactorial condition involving dysbiosis, gut-brain axis (GBA) dysfunction, visceral hypersensitivity, immune activation, and impaired gut motility and barrier integrity

GHK-Cus activation of DNA damage response networks (including ATM, BRCA1, and p53 pathways) in gene expression analyses positions it as a potential research subject for neurodegeneration prevention

observed that in pts with metastatic melanoma obesity was associated with improved survival for immunotherapy limited to male patients, with subsequent studies corroborated this sex-specific association [49, 133], suggesting that sex-linked differences in obesity may play a role regarding the obesity paradox in cancer immunotherapy