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Restricting cysteine, depleting GSH, or inhibiting GPX4 can increase phospholipid peroxidation in responsive cells, but sensitivity also depends on lipid composition, iron metabolism, parallel antioxidant systems, and tissue context (Jiang et al., 2021)
Surg Pathol Clin 14:165175 Padilla-Rodrguez AL, Bembassat M, Lazaro M, Ortiz-Hidalgo C (2007) Intra-abdominal follicular dendritic cell sarcoma with marked pleomorphic features and aberrant expression of neuroendocrine markers: report of a case with immunohistochemical analysis
Cytotoxic properties of bromelain were also tested in hepatocellular carcinoma cells (HepG2)
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