semaglutide for heart disease may reduce events more than tirzepatide Semaglutide may help treat heart

With both Mounjaro and Wegovy, the most common ones are: Nausea, particularly in the first few weeks and after each dose increase Constipation or, less often, diarrhoea Reflux and burping (occasionally with a sulphurous taste) Reduced appetite to the point of accidentally undereating Tiredness and mild headaches in the first month Dehydration if you forget to drink enough water Most of these settle within four to six weeks, especially if your dose is titrated up slowly

Metabolism , 65(2), 20-29

And when broken down by lean mass vs fat mass loss by DEXA scan it was similar to semaglutide 70% fat, 30% lean, which is also in line with bariatric surgery

Retatrutide remains investigational and is not FDA-approved, so patients should only consider it within legitimate clinical trial settings