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JZ, Y-qA, HZ, DM, and LY reviewed and edited the manuscript

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There is considerable experimental evidence showing that increased pro-oxidant production and decreased antioxidant bioavailability play an important role in the pathophysiology of hypertension and endothelial injury (11)

As cited above, a key manifestation of oxidative damage to oocytes in endometriosis is comprised by aberrations in the organization of oocyte meiotic spindles and chromosomes, a key morphologic marker for ROS damage and a widely regarded harbinger of impending oocyte and fetal aneuploidy (62, 84, 85)