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The study examined time to MACE and its components, hospitalizations for angina or heart failure, and revascularization (coronary and peripheral)

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Poly-ubiquitin chains are particularly important, as they often label target proteins to be sent to the proteasome for degradation, which is a major mechanism by which cells remove unwanted or damaged proteins

Without adequate vitamin C, collagen synthesis slows, existing collagen degrades faster, and the structural integrity of skin, blood vessels, joints, and connective tissue throughout the body deteriorates at an accelerated rate