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At any rate, considering that the main objective of any treatment for patients with CS is to reestablish normal function of the nasosinusal mucosa and the evidence that cigarette smoking impairs mucociliary transport, reducing cilia beat, the ciliogenesis or epithelial regeneration process, a proper education for these patients towards interrupting cigarette smoking as well as reinforcing campaigns against smoking are extremely important to control this disease that has a major socio-economic impact