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In order to address this question and assess whether smoking after an MS diagnosis alters the time of disease progression to SPMS, researchers conducted a study with a cohort of 728 MS Swedish patients who were smokers and participated in the Genes and Environment in Multiple Sclerosis Study, part of the Swedish National MS Registry

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Recent in vivo studies by Nath et al

In at least 29 countries, 10% or more of the population uses smokeless tobacco