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In addition, these mice had more atherosclerotic lesions than did control mice, and altered gene expression and cardiomyocyte histology accompanied this increase in atherosclerotic lesions (150)

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"These results point to the fact that nicotine exposure per se has an effect on fetal development over and above the effects of stress and depression." Reissland said the extra-movements made by the fetuses of smoking pregnancies could indicate that nicotine or other toxins from the smoke are having an effect on a fetus' development

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