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The slowed gastric emptying caused by GLP-1 medications and digestive upset directly impacts this connection, potentially leading to feelings of nausea

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System Xc - , a cystine/glutamate antiporter, functions as a transmembrane complex of light chain xCT ( SLC7A11 -encoded) and heavy chain 4F2hc ( SLC7A11 promoter correlates with higher PD susceptibility ( SLC7A11 transcription, thereby reducing xCT expression, impairing cystine uptake, and limiting intracellular GSH synthesis, ultimately heightening neuronal vulnerability to ferroptosis (92)

Al Saqr A, Aldawsari MF, Alrbyawi H, Poudel I, Annaji M, Mulabagal V, et al