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Activation of YAP can induce the expression of SLC7A11, thereby enhancing cystine uptake by System XC-, increasing GSH level, thereby increasing GPX4 synthesis, thus reducing ROS level and inhibiting ferroptosis [16, 17]

Fasting induces remodeling of the orexigenic projections from the arcuate nucleus to the hypothalamic paraventricular nucleus, in a growth hormone secretagogue receptor-dependent manner