More serious but less common risks can include: Gallbladder disease Pancreatitis Worsening of diabetic retinopathy in patients with diabetes Thyroid C-cell tumors observed in animal studies Certain conditions, medications, or risk factors may influence whether a healthcare provider thinks GLP-1s are appropriate for you, so women should review their full medical history with a qualified provider before starting therapy
The most common side effects are gastrointestinalnausea, vomiting, diarrhea, constipation, and a sense of early fullnesslargely due to delayed gastric emptying and central appetite suppression
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Based on the trial profile, it may suit people who havent lost enough weight on GLP-1-based medications, or who need the largest possible weight loss for severe obesity-related conditions