Pay in 4 interest-free payments of $5.35 Learn more
Ships within 48 hours · Estimated delivery Jul 31 - Aug 5
What should I expect during my first appointment
The Science Unveiled: Mechanism of Action NNMT and Fat Cell Metabolism: At the heart of 5-Amino 1MQs prowess lies its ability to inhibit the NNMT enzyme
Rarely a client will have itching, redness, or occasional bruising at the site of injection
Reported applications include NNMT enzyme inhibition assays measuring 1-methylnicotinamide formation or S-adenosylhomocysteine release, intracellular target-engagement assays in differentiated 3T3-L1 adipocytes where 5-Amino-1MQ reduced intracellular 1-methylnicotinamide with an EC near 2.3 M (Neelakantan et al., Biochem Pharmacol, 2018), membrane permeability and Caco-2 transport characterisation, methyltransferase selectivity panels covering COMT, DNMT1 and PRMT3, and rodent studies of NNMT inhibition in adipose tissue and liver following the antisense knockdown work of Kraus and colleagues (Nature, 2014)
US$ 26.97
US$ 21.86
US$ 25.27
