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Hypoglycemia: GLP-1 RAs showed a trend toward an increased risk of hypoglycemia across several populations

Mitochondria are engaged in the proliferation and maturation of the nervous stem cells and synaptic functions, playing a key role in the development and regulation of synaptic activity [19]

Although several agents have entered clinical evaluation, translation into durable clinical benefit remains challenging due to intratumoral heterogeneity, temporal fluctuations in oxygenation (cycling hypoxia), and adaptive resistance mechanisms that bypass single-pathway inhibition

A consensus clinical practice recommendation endorsed by the Australian Diabetes Society (ADS), National Association of Clinical Obesity Services (NACOS), Gastroenterological Society of Australia (GESA) and Australian and New Zealand College of Anaesthetists (ANZCA)