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Reference McIntyre, Woldeyohannes and SoczynskaMcIntyre 2010): longer duration of bipolar disorder, especially type I more lifetime manic and depressive episodes more severe first affective episode late onset of first manic episode late age at first treatment for manic or depressive episode

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The most common diseases caused by smoking are: Cancer including lung, blood, bladder, cervical, colon, kidney, liver, mouth and throat, and stomach cancers (among others) Heart disease and stroke Chronic obstructive pulmonary disease (COPD) Risk of pregnancy complications including foetal tissue damage and lung and brain damage Lower fertility and higher risk of miscarriage 1 Did you know that cigarette smoke is also radioactive