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Indeed, glutamine-derived R-2-HG accumulates and prevents the differentiation of myeloblasts, resulting in uncontrolled growth of blood cells 122

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(2022) provided a very comprehensive overview of animal models of PTSD and suggested modifications to simplified animal paradigms to account for myriad cognitive factors affected by PTSD, which may contribute to providing a more comprehensive recapitulation of the human experience of trauma in laboratory research (Dunsmoor et al., 2022)