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doi: 10.2337/dc16-0089 112 WhitehouseFKrugerDFFinemanMShenLRugglesJAMaggsDGet al
Plateaus Are Normal: What to Expect: Initial rapid loss (first 3 months) Continued steady loss (months 4-12) Plateau period (months 13-18) Final adjustments (months 19-24) Plateaus dont mean failure: Natural part of weight loss Body adjusting to new weight May need dose optimization Continue medication to maintain loss Non-Scale Victories: Results Beyond the Number: Even if weight loss is slower than hoped, patients experience: Reduced waist circumference: Lost inches even when scale stalls Better blood pressure: 5-10 mmHg reduction common Improved blood sugar: A1C reductions of 1-2 points Better cholesterol: 10-20% improvement in lipids Increased energy: From weight loss and metabolic improvements Improved mobility: Easier movement, less joint pain Better sleep: Improvement in sleep apnea Enhanced quality of life: Confidence, mood, relationships These improvements matter regardless of exact pounds lost
Payers should also consider the range of coverage expansion options available that best optimize the cost to plan sponsors while providing members access to these revolutionary GLP-1 drugs
