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Kidney Int 2017

The effect on heart failure must be regarded as preventive rather than curative, since dedicated trials revealed no effect on any parameter associated with heart failure [23]

The additional GIP activation provides stronger effects on insulin sensitivity and glucose metabolism, which may be particularly relevant for Hashimoto's patients dealing with insulin resistance

A large 2025 study published in Blood Advances examined more than 540,000 patients with type 2 diabetes across 21 countries and found that those taking GLP-1 medications had about a 20 percent lower risk of venous blood clots compared to those taking a different class of diabetes drug