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Even at maximum Ozempic dosing, you may notice reduced appetite suppression compared to what you experienced on higher Mounjaro doses, because youre losing the GIP receptor activity entirely

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GLP-1s, she says, might have similar effects because most women with PCOS, their obesity is so tightly linked to insulin resistance, I think they benefit more than just the average person with obesity

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Diarrhea may also occur because some GLP-1 drugs have a longer half-life meaning they stay in your system longer

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Semaglutide increases insulin secretion and improves glucose handling through GLP-1 receptor activation

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