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Familial AD is usually correlated with mutations in 3 genes encoding amyloid precursor protein (APP) and the enzymatic components of -secretase complexes, including presenilin 1 (PS1) and presenilin 2 (PS2)

A higher dose might intensify the effects and potentially shorten the onset time, but it also dramatically increases the likelihood of side effects like nausea, flushing, and headaches, which can confound the research

showed that rifaximin changed the bacterial population in the ileum of rats, increasing the relative abundance of Lactobacillus, and preventing mucosal inflammation and impaired intestinal barrier [156]

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