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l-carnitine treatment has also shown potential in the treatment of other conditions like myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS) [102], neurodegenerative diseases [103], and diabetes [49,104,105]

Therefore, considering significance of both NO-system and egr-1 gene-systems for inflammatory bowel disease (54) as well as for multiple sclerosis (55-57), these may be important also when confronted with severe complications of advanced and poorly controlled IBD as well as multiple sclerosis

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