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Ultralong tumor retention of theranostic nanoparticles with short peptide-enabled active tumor homing

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Unlike the lamina propria-residing macrophages, which sense and respond via pathogen-induced phagocytotic mechanisms to clear dying or senescent intestinal epithelial cells, muscularis macrophages present a tissue-protective phenotype by catecholamine-mediated activation of the 2-adrenergic receptor signaling pathway, triggered upon enteric infection

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