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Before taking Pepto-Bismol with Wegovy, you should: Consult your GP or prescribing clinician, particularly if symptoms are severe or persistent Check for contraindications to bismuth subsalicylate (such as aspirin/salicylate allergy, bleeding disorders, kidney problems, pregnancy, breastfeeding, or if under 16 years of age) Consider whether your symptoms might be better managed through Wegovy dose adjustment Avoid prolonged use of Pepto-Bismol without medical advice Be aware that bismuth can cause harmless darkening of stools and tongue, which should not be confused with bleeding If gastrointestinal symptoms are significantly impacting your quality of life, contact your healthcare provider rather than relying solely on over-the-counter remedies

The conflicting safety signal One real-world evidence study found that patients receiving GLP-1 receptor agonists had higher risks of certain autoimmune conditions, including ulcerative colitis, rheumatoid arthritis, autoimmune thyroiditis, ankylosing spondylitis, and psoriasis, compared to those on DPP-4 inhibitors

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Bucklew, whose coverage was denied, would still like to resume Ozempic