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Cysteine starved PDAC cells undergo plasma membrane destabilization and show significantly increased levels of lipid peroxidation, a signature of cells undergoing ferroptosis

Methylene blue is used to treat UTI symptoms as an antiseptic and mild analgesic in some oral medications, reducing discomfort and bacterial growth

Igf-1r activation is reported to suppress inflammation in the TME of NSCLC models 39 and induce degradation of retinoic acid-inducible gene-I (RIG1), a pattern-recognition receptor required for type 1 IFN production and the proper function of the innate immune response 40