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Conversely, injectable formulations may remain preferable for patients who prioritize once-weekly dosing over daily administration, individuals whose schedules or circumstances make consistent empty-stomach morning dosing challenging, those for whom predictable high bioavailability is clinically important, patients with gastrointestinal conditions potentially affecting oral drug absorption, and individuals who previously responded well to injectable therapy and see no reason to change administration routes

Fras JP, et al

GLP-1 treatments