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Signs of severe dehydration, such as extreme thirst or dark urine

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Additionally, blocking of Wnt/-catenin activation in DPCs reduced the expression of the growth factors vegf and fgf7 (Fig

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If glucose levels are very high SGLT2 inhibitors can result in marked polyuria and nocturia that leads to uncomfortable symptoms and therefore many clinicians do not initiate SGLT2 inhibitor therapy in patients with high HbA1c levels until glucose control is in a more reasonable range

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M.MedcalfR

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